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If caffeine caused weight loss, then 80% of americans would be skinny

Key points Caffeine ruins your sleep, which causes overeating

Caffeine raises stress hormones, causing overeating

Caffeine raises dopamine, causing pleasure cravings

Rebound energy and mood swings cause overeating

Lowered adrenal function degreases sex hormones, making you feel miserable, which further causes overeating

Caffeine lowers bloodflow to the pre-frontal cortex, making you impulsive and stupid.

https://www.youtube.com/watch?v=jqcnfYfYYdY

https://pmc.ncbi.nlm.nih.gov/articles/PMC2748160/

https://www.adrenal.com/blog/the-dangers-of-excess-cortisol-understanding-hypercortisolism-and-its-complications

https://www.sciencedirect.com/science/article/abs/pii/S0195666305001133?via%3Dihub

https://pmc.ncbi.nlm.nih.gov/articles/PMC2249754/

https://pubmed.ncbi.nlm.nih.gov/27345309/

https://pubmed.ncbi.nlm.nih.gov/8951977/


Adenosine dampens or slows down neuron firing. It acts like a fuse box to prevent your circuits from getting overloaded. When caffeine inactivates this control mechanism, your neuron circuits keep firing, and you feel alert. The problem is, your circuits keep firing, and firing, and firing.…

Uncontrolled neuron firing creates an emergency situation, which triggers the pituitary gland in the brain to secrete ACTH (adrenocorticotrophic hormone). https://pubmed.ncbi.nlm.nih.gov/8951977/

ACTH tells the adrenal glands to pump out stress hormones—the next major side effect of caffeine. A single 250-milligram dose of caffeine (the equivalent of about 21/2 six-ounce cups of coffee) has been shown to increase levels of the stress hormone epi-nephrine (commonly known as adrenaline) by more than 200 percent.

Caffeine also stimulates the production of norepinephrine, another stress hormone that acts directly on the brain and nervous system. Epinephrine and norepinephrine are responsible for increased heart rate, increased blood pressure, and that “emergency” feeling. In fact, the emergency is quite real.


lowers the stress threshold so that events we would normally handle suddenly become insurmountable.


stress stimulates neuron activity in the primitive part of the brain known as the limbic system. However, the vast majority of problems we face today require reason, imagination, and creativity: all functions of the “higher brain” or cerebrum.


The sugar and fat that are dumped into your bloodstream go unused. The sugar creates additional metabolic stress, and the fat clogs your arteries.


And since blood flow has been diverted from the gastrointestinal tract, the food you just ate is converted to a fermenting and putrefying mass.

Caffeine is a major contributor to the bloating, pain, and gas that roughly 50 percent of American adults experience after they eat.

Unseen are the harmful by-products of fermentation and putrefaction.

Some of these by-products are absorbed back into the bloodstream, and the toxins that stay in the gut increase your risk of gastrointestinal disease.

There’s no reason to digest your breakfast if you are about to become lunch.…

\[Under stress\]

a whole series of maintenance and repair activities just stop.


Body must then deal with the metabolic emergency of hyperglycemia (elevated blood sugar). This is accomplished by the pancreas, which secrets insulin, driving the blood-sugar level down.

In some individuals, however, blood sugar may decrease to levels below normal, resulting in hypoglycemia and the all-too-familiar “letdown” feeling a few hours after the coffee lift.


loss of calcium, magnesium, sodium, and chloride in the urine. folic acid, vitamin B-12, and vitamin B-6 Zinc was added to the list of nutrients depleted by caffeine. thiamin potassium decreased bioavailability of protein A single cup of coffee can reduce iron absorption from a meal by as much as 75 percent.

Low iron can seriously affect energy, immunity, and even brain function long before anemia develops.

Caffeine resulted in significantly lower levels of melatonin.


The stress response causes a shift of mental function to a very primitive survival-oriented part of the brain known as the limbic system.


Caffeine causes a remarkable decrease in cerebral blood flow.


As sleep improves, you would expect an increase in energy, but the ripple effect of benefits also included decreased pain, better mood, decreased reliance on prescription and over-the-counter drugs, enhanced immune function, and improvements in memory and learning.


Coffee may also speed gastric emptying, meaning that the contents of the stomach are passed prematurely into the small intestine, cutting short the important gastric phase of the digestive process.


Caffeine raises blood sugar levels and disrupts the blood sugar-regulating effect of insulin.

Has been shown to produce transient insulin resistance that is very similar to Type II diabetes.

Caffeine raises fatty acid levels in the blood.


Caffeine is associated with decreases in levels of estradiol.


People tend to crave fat when their stress hormone levels are elevated.


The more/faster dopamine released from a drug or behavior, the more addictive the drug or behavior is.

Pleasure and pain function as a balance in the brain. When one side of the balance is weighted down, the brain compensates by pushing down on the opposite side. Pleasure leads to pain, pain leads to pleasure.

The brain wants to maintain homeostasis.

Opponent process theory states that any prolonged or repeated departures from hedonic or effective neutrality have a cost.

With prolonged exposure to pleasure, our capacity to tolerate pain decreases, and our threshold for experiencing pleasure increases.


The negative feedback caused by tolerance
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Repeated exposure to a pleasure stimulus makes the pleasure from that stimulus less and less. And the rebound to the pain side gets stronger and longer. You need more of a behavior or substance over time to feel the same amount of pleasure.

Over time, your baseline gets set to the side of pain, as your brain tries to counteract bigger and more potent doses of pleasure.